RARE DISEASES

At Sterling Analytics, we understand the critical challenges and urgency that come with rare disease research. With fewer than 200,000 Americans affected by each condition, rare diseases demand specialized statistical strategies that maximize small datasets, support innovative trial designs, and meet stringent regulatory requirements.

Our rare disease expertise includes adaptive and Bayesian design approaches, integrated biomarker strategies, and collaborative engagement with patient advocacy groups and registries.

With every trial, Sterling Analytics delivers precision analytics to power rare disease innovation—turning small data into meaningful breakthroughs for underserved populations.

Our areas of expertise:

🟣Limb-Girdle Muscular Dystrophy (LGMD)

LGMD is a progressive neuromuscular disorder with significant variability in onset, severity, and progression. We support clinical trials for LGMD with:

  • Customized natural history modeling

  • Functional outcome measure analysis (e.g., 6MWT, NSAA, PROMs)

  • Statistical support for gene therapy, biologic, and supportive treatment trials